Efficient conversion of N6-threonylcarbamoyladenosine (t6A) into a tRNA native hydantoin cyclic form (ct6A) performed at nucleoside and oligoribonucleotide levels.
Identifieur interne : 000E10 ( Main/Exploration ); précédent : 000E09; suivant : 000E11Efficient conversion of N6-threonylcarbamoyladenosine (t6A) into a tRNA native hydantoin cyclic form (ct6A) performed at nucleoside and oligoribonucleotide levels.
Auteurs : Michal Matuszewski [Pologne] ; Katarzyna Debiec ; Elzbieta SochackaSource :
- Chemical communications (Cambridge, England) [ 1364-548X ] ; 2017.
Descripteurs français
- KwdFr :
- ARN de transfert de la lysine (), ARN de transfert de la lysine (synthèse chimique), Adénosine (), Adénosine (analogues et dérivés), Anticodon, Carbodiimides (), Concentration en ions d'hydrogène, Cyclisation, Escherichia coli, Hydantoïnes (), Hydantoïnes (synthèse chimique), Oligoribonucléotides (), Oligoribonucléotides (synthèse chimique), Schizosaccharomyces, Stabilité de l'ARN.
- MESH :
- analogues et dérivés : Adénosine.
- synthèse chimique : ARN de transfert de la lysine, Hydantoïnes, Oligoribonucléotides.
- ARN de transfert de la lysine, Adénosine, Anticodon, Carbodiimides, Concentration en ions d'hydrogène, Cyclisation, Escherichia coli, Hydantoïnes, Oligoribonucléotides, Schizosaccharomyces, Stabilité de l'ARN.
English descriptors
- KwdEn :
- Adenosine (analogs & derivatives), Adenosine (chemistry), Anticodon, Carbodiimides (chemistry), Cyclization, Escherichia coli, Hydantoins (chemical synthesis), Hydantoins (chemistry), Hydrogen-Ion Concentration, Oligoribonucleotides (chemical synthesis), Oligoribonucleotides (chemistry), RNA Stability, RNA, Transfer, Lys (chemical synthesis), RNA, Transfer, Lys (chemistry), Schizosaccharomyces.
- MESH :
- chemical , analogs & derivatives : Adenosine.
- chemical , chemical synthesis : Hydantoins, Oligoribonucleotides, RNA, Transfer, Lys.
- chemical , chemistry : Adenosine, Carbodiimides, Hydantoins, Oligoribonucleotides, RNA, Transfer, Lys.
- chemical : Anticodon.
- Cyclization, Escherichia coli, Hydrogen-Ion Concentration, RNA Stability, Schizosaccharomyces.
Abstract
A t6A nucleoside was efficiently and stereospecifically transformed into a hydantoin cyclic form of N6-l-threonylcarbamoyladenosine (ct6A) by the use of polymer bounded carbodiimide (EDC-P) and HOBt. The procedure was successfully applied for a post-synthetic conversion of t6A-containing RNA 17-mers (of the sequences of anticodon stem and loop (ASL) fragments of S. pombe tRNAi and E. coli tRNALys) into the products bearing the ct6A unit.
DOI: 10.1039/c7cc03560h
PubMed: 28657616
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000C42
- to stream PubMed, to step Curation: 000C42
- to stream PubMed, to step Checkpoint: 000D24
- to stream Ncbi, to step Merge: 001A93
- to stream Ncbi, to step Curation: 001A93
- to stream Ncbi, to step Checkpoint: 001A93
- to stream Main, to step Merge: 000E13
- to stream Main, to step Curation: 000E10
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Efficient conversion of N<sup>6</sup>-threonylcarbamoyladenosine (t<sup>6</sup>A) into a tRNA native hydantoin cyclic form (ct<sup>6</sup>A) performed at nucleoside and oligoribonucleotide levels.</title><author><name sortKey="Matuszewski, Michal" sort="Matuszewski, Michal" uniqKey="Matuszewski M" first="Michal" last="Matuszewski">Michal Matuszewski</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Organic Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland. elzbieta.sochacka@p.lodz.pl.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Institute of Organic Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz</wicri:regionArea><wicri:noRegion>90-924 Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Debiec, Katarzyna" sort="Debiec, Katarzyna" uniqKey="Debiec K" first="Katarzyna" last="Debiec">Katarzyna Debiec</name></author><author><name sortKey="Sochacka, Elzbieta" sort="Sochacka, Elzbieta" uniqKey="Sochacka E" first="Elzbieta" last="Sochacka">Elzbieta Sochacka</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28657616</idno><idno type="pmid">28657616</idno><idno type="doi">10.1039/c7cc03560h</idno><idno type="wicri:Area/PubMed/Corpus">000C42</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000C42</idno><idno type="wicri:Area/PubMed/Curation">000C42</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000C42</idno><idno type="wicri:Area/PubMed/Checkpoint">000D24</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000D24</idno><idno type="wicri:Area/Ncbi/Merge">001A93</idno><idno type="wicri:Area/Ncbi/Curation">001A93</idno><idno type="wicri:Area/Ncbi/Checkpoint">001A93</idno><idno type="wicri:Area/Main/Merge">000E13</idno><idno type="wicri:Area/Main/Curation">000E10</idno><idno type="wicri:Area/Main/Exploration">000E10</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Efficient conversion of N<sup>6</sup>-threonylcarbamoyladenosine (t<sup>6</sup>A) into a tRNA native hydantoin cyclic form (ct<sup>6</sup>A) performed at nucleoside and oligoribonucleotide levels.</title><author><name sortKey="Matuszewski, Michal" sort="Matuszewski, Michal" uniqKey="Matuszewski M" first="Michal" last="Matuszewski">Michal Matuszewski</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Organic Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland. elzbieta.sochacka@p.lodz.pl.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Institute of Organic Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz</wicri:regionArea><wicri:noRegion>90-924 Lodz</wicri:noRegion></affiliation></author><author><name sortKey="Debiec, Katarzyna" sort="Debiec, Katarzyna" uniqKey="Debiec K" first="Katarzyna" last="Debiec">Katarzyna Debiec</name></author><author><name sortKey="Sochacka, Elzbieta" sort="Sochacka, Elzbieta" uniqKey="Sochacka E" first="Elzbieta" last="Sochacka">Elzbieta Sochacka</name></author></analytic><series><title level="j">Chemical communications (Cambridge, England)</title><idno type="eISSN">1364-548X</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenosine (analogs & derivatives)</term><term>Adenosine (chemistry)</term><term>Anticodon</term><term>Carbodiimides (chemistry)</term><term>Cyclization</term><term>Escherichia coli</term><term>Hydantoins (chemical synthesis)</term><term>Hydantoins (chemistry)</term><term>Hydrogen-Ion Concentration</term><term>Oligoribonucleotides (chemical synthesis)</term><term>Oligoribonucleotides (chemistry)</term><term>RNA Stability</term><term>RNA, Transfer, Lys (chemical synthesis)</term><term>RNA, Transfer, Lys (chemistry)</term><term>Schizosaccharomyces</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN de transfert de la lysine ()</term><term>ARN de transfert de la lysine (synthèse chimique)</term><term>Adénosine ()</term><term>Adénosine (analogues et dérivés)</term><term>Anticodon</term><term>Carbodiimides ()</term><term>Concentration en ions d'hydrogène</term><term>Cyclisation</term><term>Escherichia coli</term><term>Hydantoïnes ()</term><term>Hydantoïnes (synthèse chimique)</term><term>Oligoribonucléotides ()</term><term>Oligoribonucléotides (synthèse chimique)</term><term>Schizosaccharomyces</term><term>Stabilité de l'ARN</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Adenosine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemical synthesis" xml:lang="en"><term>Hydantoins</term><term>Oligoribonucleotides</term><term>RNA, Transfer, Lys</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Adenosine</term><term>Carbodiimides</term><term>Hydantoins</term><term>Oligoribonucleotides</term><term>RNA, Transfer, Lys</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Anticodon</term></keywords><keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr"><term>Adénosine</term></keywords><keywords scheme="MESH" qualifier="synthèse chimique" xml:lang="fr"><term>ARN de transfert de la lysine</term><term>Hydantoïnes</term><term>Oligoribonucléotides</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cyclization</term><term>Escherichia coli</term><term>Hydrogen-Ion Concentration</term><term>RNA Stability</term><term>Schizosaccharomyces</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>ARN de transfert de la lysine</term><term>Adénosine</term><term>Anticodon</term><term>Carbodiimides</term><term>Concentration en ions d'hydrogène</term><term>Cyclisation</term><term>Escherichia coli</term><term>Hydantoïnes</term><term>Oligoribonucléotides</term><term>Schizosaccharomyces</term><term>Stabilité de l'ARN</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A t<sup>6</sup>A nucleoside was efficiently and stereospecifically transformed into a hydantoin cyclic form of N<sup>6</sup>-l-threonylcarbamoyladenosine (ct<sup>6</sup>A) by the use of polymer bounded carbodiimide (EDC-P) and HOBt. The procedure was successfully applied for a post-synthetic conversion of t<sup>6</sup>A-containing RNA 17-mers (of the sequences of anticodon stem and loop (ASL) fragments of S. pombe tRNA<sup>i</sup> and E. coli tRNA<sup>Lys</sup>) into the products bearing the ct<sup>6</sup>A unit.</div></front></TEI><affiliations><list><country><li>Pologne</li></country></list><tree><noCountry><name sortKey="Debiec, Katarzyna" sort="Debiec, Katarzyna" uniqKey="Debiec K" first="Katarzyna" last="Debiec">Katarzyna Debiec</name><name sortKey="Sochacka, Elzbieta" sort="Sochacka, Elzbieta" uniqKey="Sochacka E" first="Elzbieta" last="Sochacka">Elzbieta Sochacka</name></noCountry><country name="Pologne"><noRegion><name sortKey="Matuszewski, Michal" sort="Matuszewski, Michal" uniqKey="Matuszewski M" first="Michal" last="Matuszewski">Michal Matuszewski</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E10 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000E10 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:28657616
|texte= Efficient conversion of N6-threonylcarbamoyladenosine (t6A) into a tRNA native hydantoin cyclic form (ct6A) performed at nucleoside and oligoribonucleotide levels.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28657616" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |